A Modified Triester Method for the Synthesis of Deoxyribopolynucleotides

K. ITAKURA, Chander P. Bahl, N. KATAGIRI, J.J. Michniewicz, R. H. WIGHTMAN, Saran A. Narang

Canadian Journal of Chemistry · 1973 · 71 citations · 0 references

Concepts

Abstract

A modified triester method has been developed for the synthesis of oligonucleotides starting from mononucleosides as more economical starting materials. A pentadecanucleotide has been successfully prepared.