Comparison of the Antinociceptive Profiles of Gabapentin and 3-Methylgabapentin in Rat Models of Acute and Persistent Pain: Implications for Mechanism of Action

Quantitative assessment of tactile allodynia in the rat paw

Sandra R. Chaplan, Flemming W. Bach, J W Pogrel et al. · Journal of Neuroscience Methods · 1994 · 7.9K citations

Life Sciences, Neurobiology, Neuroscience +12

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Kenneth Hargreaves, Ronald Dubner, Frederick J. Brown et al. · Pain · 1988 · 5.2K citations

Medicine, Pharmacology, Behavioral Pharmacology +16

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

Sun Ho Kim, Jin Mo Chung · Pain · 1992 · 3K citations

Medicine, Neurology, Neuroscience +17

The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats

David Dubuisson, Stephen G. Dennis · Pain · 1977 · 2.5K citations

Medicine, Neuroscience, Pharmacology +17

The Novel Anticonvulsant Drug, Gabapentin (Neurontin), Binds to the α2δ Subunit of a Calcium Channel

N S Gee, Jason P. Brown, Visaka U.K. Dissanayake et al. · Journal of Biological Chemistry · 1996 · 1.2K citations · Full text

Medicine, Neuroscience, Pharmacology +15