The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension - Concepedia

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The PPARβ/δAgonist GW0742 Relaxes Pulmonary Vessels and Limits Right Heart Hypertrophy in Rats with Hypoxia-Induced Pulmonary Hypertension

DOI Full Paper Access

46

Citations

29

References

2010

Year

Louise S. Harrington, Laura Moreno, Anna Reed, Stephen J. Wort, Béatrice Desvergne, C J Garland, Lan Zhao, Jane A. Mitchell

Abstract

These observations are the first to show a therapeutic benefit of 'PPARbeta/delta' agonists in experimental pulmonary arterial hypertension and provide pre-clinical evidence to favour clinical trials in man.

References

	Year	Citations

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