Prevalence, Correlates, and Outcomes of Cryptococcal Antigen Positivity Among Patients With AIDS, United States, 1986–2012

Abstract

The prevalence of cryptococcal infection among advanced AIDS patients in the United States was high and above the published cost-effectiveness threshold for routine screening. We recommend routine CrAg screening among human immunodeficiency virus-infected patients with a CD4 count ≤100 cells/µL to detect and treat early infection.