The first total synthesis of trichostatin D

Potent and specific inhibition of mammalian histone deacetylase both in vivo and in vitro by trichostatin A.

Minoru Yoshida, Masako Kijima, Motomu Akita et al. · Journal of Biological Chemistry · 1990 · 1.9K citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Simple, Efficient Catalyst System for the Palladium-Catalyzed Amination of Aryl Chlorides, Bromides, and Triflates

John P. Wolfe, Hiroshi Tomori, Joseph P. Sadighi et al. · The Journal of Organic Chemistry · 2000 · 683 citations

Natural Sciences, Chemistry, Catalysis +16

A new antifungal antibiotic, trichostatin.

Naoki Tsuji, Masaaki Kobayashi, K. Nagashima et al. · The Journal of Antibiotics · 1976 · 336 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Mechanism of Cell Cycle Arrest Caused by Histone Deacetylase Inhibitors in Human Carcinoma Cells.

Young Bae Kim, Se Won Ki, MINORU YOSNIDA et al. · The Journal of Antibiotics · 2000 · 123 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

Synthesis of trichostatin a, a potent differentiation inducer of friend leukemic cells, and its antipode

Kenji Mori, Koshi Koseki · Tetrahedron · 1988 · 77 citations

Medicine, Cancer Biology, Oncology +5