Ranitidine Treatment during a Modest Inflammatory Response Precipitates Idiosyncrasy-Like Liver Injury in Rats

Neutrophil depletion protects against liver injury from bacterial endotoxin.

James A. Hewett, A. Eric Schultze, S VanCise et al. · PubMed · 1992 · 178 citations

Life Sciences, Immunology, Microbiology +16

Underlying Endotoxemia Augments Toxic Responses to Chlorpromazine: Is There a Relationship to Drug Idiosyncrasy?

John P. Buchweitz, Patricia E. Ganey, Steven J. Bursian et al. · Journal of Pharmacology and Experimental Therapeutics · 2002 · 132 citations

Medicine, Pharmacology, Toxicology +14

Synergistic Hepatotoxicity from Coexposure to Bacterial Endotoxin and the Pyrrolizidine Alkaloid Monocrotaline

Steven B. Yee, Shawn Kinser, Dwayne A. Hill et al. · Toxicology and Applied Pharmacology · 2000 · 94 citations

Pharmacy, Pharmacology, Toxicology +16

Identification of factors from rat neutrophils responsible for cytotoxicity to isolated hepatocytes

John S. Ho, John P. Buchweitz, Robert A. Roth et al. · Journal of Leukocyte Biology · 1996 · 84 citations

Veterinary Medicine, Immunology, Pathobiology +15

Bacterial Lipopolysaccharide Enhances Aflatoxin B1 Hepatotoxicity in Rats by A Mechanism That Depends on Tumor Necrosis Factor α

Charles C. Barton, Eva X. Barton, Patricia E. Ganey et al. · Hepatology · 2001 · 83 citations · Full text

Pharmacy, Immunology, Toxicology +14