Concepedia

Idiosyncratic Toxicity

Idiosyncratic Toxicity is a type of adverse drug reaction characterized by its unpredictable occurrence in a small subset of individuals, not dose-dependent, and often mediated by reactive metabolite formation leading to immune activation or cellular damage.

199

Publications

12.2K

Citations

804

Authors

255

Institutions

Publications per year

2017–2026

28

Parents

Publications

199

Results of a Prospective Study of Acute Liver Failure at 17 Tertiary Care Centers in the United States

George Ostapowicz, Robert J. Fontana, Frank Vinholt Schiødt et al. · Annals of Internal Medicine · 2002 · 2.2K citations

, , +14

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Jinghai J. Xu, Peter Henstock, Margaret C. Dunn et al. · Toxicological Sciences · 2008 · 492 citations · Full text

, , +17

Etiology and outcome for 295 patients with acute liver failure in the united states

Frank Vinholt Schiødt, Evren Atillasoy, Amer Shakil et al. · Liver Transplantation and Surgery · 1999 · 401 citations · Full text

, , +15

Acute liver failure: Clinical features, outcome analysis, and applicability of prognostic criteria

A. Obaid Shakil, David J. Kramer, George Mazariegos et al. · Liver Transplantation · 2000 · 329 citations · Full text

, , +16

A Zone Classification System for Risk Assessment of Idiosyncratic Drug Toxicity Using Daily Dose and Covalent Binding

Shintaro Nakayama, Ryo Atsumi, Hideo Takakusa et al. · Drug Metabolism and Disposition · 2009 · 248 citations

, , +17

1–5 of 199

Authors

804

  1. PE
    Patricia E. Ganey

    Michigan State University, United States

    15 publications · 1.1K citations

    15

    h-index

  2. RA
    Robert A. Roth

    Michigan State University, United States

    15 publications · 1.1K citations

    15

    h-index

  3. JU
    Jack Uetrecht

    University of Toronto, Canada

    14 publications · 637 citations

    13

    h-index

  4. XX
    Xiaohe Xiao

    Chinese People's Liberation Army, China

    8 publications · 423 citations

    8

    h-index

  5. JF
    Jane F. Maddox

    Michigan State University, United States

    6 publications · 557 citations

    6

    h-index

1–5 of 804

Institutions

255

  1. University of Toronto

    Toronto, Canada

    15 h-index

    47 publications

    2.2K citations

  2. Michigan State University

    East Lansing, United States

    15 h-index

    58 publications

    4.2K citations

  3. Pfizer (United States)

    New York, United States

    13 h-index

    43 publications

    4.9K citations

  4. Chinese People's Liberation Army

    Beijing, China

    6 h-index

    56 publications

    3.5K citations

  5. University of Washington

    Seattle, United States

    6 h-index

    16 publications

    1.1K citations

  6. Institute of Pharmacology

    Prague, Czechia

    5 h-index

    12 publications

    958 citations

  7. Abbott Fund

    Chicago, United States

    4 h-index

    19 publications

    2K citations

  8. Capital Medical University

    Beijing, China

    4 h-index

    5 publications

    278 citations

1–8 of 255

Venues

  1. Drug Metabolism and Disposition

    14 publications · 1.1K citations

    14

    h-index

  2. PubMed

    Repository · 18 publications · 551 citations

    13

    h-index

  3. Chemical Research in Toxicology

    16 publications · 791 citations

    13

    h-index

  4. Toxicological Sciences

    10 publications · 1K citations

    10

    h-index

  5. 8

    h-index

1–5