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Celastrol, a novel HSP90 inhibitor, depletes Bcr–Abl and induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation

Hematological MalignancyT315i MutationMedicineInduces ApoptosisNovel Hsp90 InhibitorImmunologyCell DeathOncologyCell BiologyCancer ResearchTumor BiologyMyeloid Neoplasia