Jingxuan Pan

Antineoplastic Mechanisms of Niclosamide in Acute Myelogenous Leukemia Stem Cells: Inactivation of the NF-κB Pathway and Generation of Reactive Oxygen Species

Yanli Jin, Zhongzheng Lu, Ke Ding et al. · Cancer Research · 2010 · 332 citations · Full text

Chemoprevention Strategy, Apoptosis, Immunology +19

Identification of Niclosamide as a New Small-Molecule Inhibitor of the STAT3 Signaling Pathway

Xiaomei Ren, Lei Duan, Qiang He et al. · ACS Medicinal Chemistry Letters · 2010 · 225 citations · Full text

Chemoprevention Strategy, Immunology, Pharmacotherapy +20

Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway

Dongmei Zhang, Jun-Shan Liu, Lijuan Deng et al. · Carcinogenesis · 2013 · 213 citations · Full text

Identification of GZD824 as an Orally Bioavailable Inhibitor That Targets Phosphorylated and Nonphosphorylated Breakpoint Cluster Region–Abelson (Bcr-Abl) Kinase and Overcomes Clinically Acquired Mutation-Induced Resistance against Imatinib

Xiaomei Ren, Xiaofen Pan, Zhang Zhang et al. · Journal of Medicinal Chemistry · 2013 · 174 citations · Full text

Targeting methyltransferase PRMT5 eliminates leukemia stem cells in chronic myelogenous leukemia

Yanli Jin, Jingfeng Zhou, Fang Xu et al. · Journal of Clinical Investigation · 2016 · 165 citations · Full text

Epigenetic Change, Mixed-phenotype Acute Leukemia, Chronic Myelogenous Leukemia +19