Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva, +5

Nature

Synaptic PlasticityAlzheimer's DiseaseMolecular NeuroscienceAmyloid β ProteinMedicine +5

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy, +12

Proceedings of the National Academy of Sciences

RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory

Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, +5

Nature

Neurodegenerative DiseasesCognitive ScienceBrain FunctionMedicineMemory Loss +10

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda, +5

Immunity

InflammationCytokineImmunogeneticsImmune Cell DevelopmentMyd88 Gene Results +9

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson, +9

Human Molecular Genetics

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

Cameron R. Stewart, Lynda M. Stuart, Kim Wilkinson, +11

Nature Immunology

InflammationToll-like ReceptorsMolecular ImmunologyAutoimmune DiseaseMedicine +8

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Dianhua Jiang, Jiurong Liang, Juan Fan, +13

Nature Medicine

InflammationToll-like ReceptorsAsthmaAcute Lung InjuryInflammatory Lung Disease +11

Clearance of Alzheimer’s amyloid-β1-40 peptide from brain by LDL receptor–related protein-1 at the blood-brain barrier

Masayoshi Shibata, Shinya Yamada, S. Ram Kumar, +8

Journal of Clinical Investigation

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

Warren J. Strittmatter, Karl H. Weisgraber, Daoyuan Huang, +7

Proceedings of the National Academy of Sciences

Metabolic Regulation of Brain Aβ by Neprilysin

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, +7

Science

AgingNeurochemical BiomarkersAmyloid Beta PeptideAlzheimer's DiseaseNeurology +17