MyD88 Deficiency Ameliorates β-Amyloidosis in an Animal Model of Alzheimer's Disease

Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

Dominic M. Walsh, Igor Klyubin, Julia V. Fadeeva et al. · Nature · 2002 · 4.3K citations

Life Sciences, Neurobiology, Neuroscience +14

Diffusible, nonfibrillar ligands derived from Aβ _1–42 are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

RETRACTED ARTICLE: A specific amyloid-β protein assembly in the brain impairs memory

Sylvain Lesné, Ming Teng Koh, Linda Kotilinek et al. · Nature · 2006 · 2.8K citations

Life Sciences, Neurobiology, Neuroscience +16

Targeted Disruption of the MyD88 Gene Results in Loss of IL-1- and IL-18-Mediated Function

Osamu Adachi, Taro Kawai, Kiyoshi Takeda et al. · Immunity · 1998 · 2K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16