Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions

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Genetics, Molecular Biology, Metabolic Model +20

A vision for the future of genomics research

Francis S. Collins, Eric D. Green, Alan E. Guttmacher et al. · Nature · 2003 · 1.7K citations · Full text

Functional Genomics, Next-generation Sequencing, Genetics +8

Analysis of optimality in natural and perturbed metabolic networks

Daniel Segrè, Dennis Vitkup, George M. Church · Proceedings of the National Academy of Sciences · 2002 · 1.4K citations · Full text

Engineering, Escherichia Coli, Network Analysis +20

Understanding the control of metabolism

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Metabolic Network, Systems Biology, Biochemistry +12

Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110

Amit Varma, Bernhard Ø. Palsson · Applied and Environmental Microbiology · 1994 · 1.1K citations · Full text

Engineering, Balance Models, Flux Balance Model +21