Concepedia

Epithelial–mesenchymal transition and mesenchymal–epithelial transition via regulation of ZEB‐1 and ZEB‐2 expression in pancreatic cancer

Hiroshi Kurahara, Sonshin Takao, Kosei Maemura, Yuko Mataki, Taisaku Kuwahata, Koki Maeda, Qiang Ding, Masahiko Sakoda, Satoshi Iino, Sumiya Ishigami,

Journal of Surgical Oncology · 2011 · 103 citations · 21 references

DOI

Abstract

In primary pancreatic tumors and metastatic lymph nodes, high and low expression of ZEB-1 and ZEB-2 was associated with mesenchymal and epithelial phenotype of cancer cells, respectively.

References

21

A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells

Ulrike Burk, Jörg Schubert, Ulrich F. Wellner et al. · EMBO Reports · 2008 · 1.7K citations · Full text

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The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2

Manav Korpal, Esther S. Lee, Guohong Hu et al. · Journal of Biological Chemistry · 2008 · 1.6K citations · Full text

The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

Joke Comijn, Geert Berx, Petra Vermassen et al. · Molecular Cell · 2001 · 1.4K citations · Full text

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A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

Cameron P. Bracken, Philip A. Gregory, Natasha Kolesnikoff et al. · Cancer Research · 2008 · 1.1K citations · Full text

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

Thiruvengadam Arumugam, Vijaya Ramachandran, Keith F. Fournier et al. · Cancer Research · 2009 · 856 citations · Full text

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