Prevalence and pattern of perceived intelligibility changes in Parkinson's disease

TLDR

Changes to spoken communication are inevitable in Parkinson's disease (PD). The study aims to determine the prevalence of impaired speech intelligibility in PD and its association with disease progression indicators. The study recruited 125 PD speakers and matched controls, who performed a diagnostic intelligibility test and a task describing a daily activity in an off‑drug state, with listeners unfamiliar with dysarthria evaluating the responses. Approximately 70 % of PD participants had intelligibility below the control mean, with over half more than one standard deviation below, and nearly half perceived their speech as worse than the lowest unaffected speaker; speech intelligibility was a major concern for 38 % of participants, yet it showed no significant correlation with age, disease duration, or motor phenotype, and patients’ subjective perceptions often did not match objective measures.

Abstract

Changes to spoken communication are inevitable in Parkinson's disease (PD). It remains unclear what consequences changes have for intelligibility of speech.To establish the prevalence of impaired speech intelligibility in people with PD and the relationship of intelligibility decline to indicators of disease progression.125 speakers with PD and age matched unaffected controls completed a diagnostic intelligibility test and described how to carry out a common daily activity in an "off drug" state. Listeners unfamiliar with dysarthric speech evaluated responses.69.6% (n = 87) of people with PD fell below the control mean of unaffected speakers (n = 40), 51.2% (n = 64) by more than -1 SD below. 48% (n = 60) were perceived as worse than the lowest unaffected speaker for how disordered speech sounded. 38% (n = 47) placed speech changes among their top four concerns regarding their PD. Intelligibility level did not correlate significantly with age or disease duration and only weakly with stage and severity of PD. There were no significant differences between participants with tremor dominant versus postural instability/gait disorder motor phenotypes of PD.Speech intelligibility is significantly reduced in PD; it can be among the main concerns of people with PD, but it is not dependent on disease severity, duration or motor phenotype. Patients' own perceptions of the extent of change do not necessarily reflect objective measures.