Correlation of White Matter Diffusivity and Anisotropy with Age during Childhood and Adolescence: A Cross-sectional Diffusion-Tensor MR Imaging Study

Abstract

Diffusion-tensor MR imaging results indicate that white matter maturation assessed at different ages involves increases in both white matter density and organization during childhood and adolescence. The trace of the apparent diffusion coefficient and fractional anisotropy may reflect different physiologic processes in healthy children and adolescents.