Concepedia

Rosuvastatin Alleviates Diabetic Cardiomyopathy by Inhibiting NLRP3 Inflammasome and MAPK Pathways in a Type 2 Diabetes Rat Model

Beibei Luo, Bo Li, Wenke Wang, Xiangjuan Liu, Xiaoman Liu, Yanfei Xia, Cheng Zhang, Yun Zhang, Mingxiang Zhang, Fengshuang An

Cardiovascular Drugs and Therapy · 2013 · 149 citations · 30 references

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30

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

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IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Alana G. Lerner, John-Paul Upton, Paurush Praveen et al. · Cell Metabolism · 2012 · 832 citations · Full text

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Omega-3 Fatty Acids Prevent Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome Activation

Yiqing Yan, Wei Jiang, Thibaud Spinetti et al. · Immunity · 2013 · 756 citations · Full text

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Cannabinoid 1 Receptor Promotes Cardiac Dysfunction, Oxidative Stress, Inflammation, and Fibrosis in Diabetic Cardiomyopathy

Mohanraj Rajesh, Sándor Bátkai, Malek Kechrid et al. · Diabetes · 2012 · 249 citations · Full text

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Mechanisms of disease: inflammasome activation and the development of type 2 diabetes

Ryan W. Grant, Vishwa Deep Dixit · Frontiers in Immunology · 2013 · 210 citations · Full text

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