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Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-α converting enzyme (TACE): Discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1′ substituents

Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural SciencesPyrazolopyridine P1′ SubstituentsPharmacological AgentBioavailable InhibitorsPharmacotherapyAnti-cancer AgentDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery