Hydrogen-Rich Saline Protects Against Renal Ischemia/Reperfusion Injury in Rats

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals

Ikuroh Ohsawa, Masahiro Ishikawa, Kumiko Takahashi et al. · Nature Medicine · 2007 · 2.5K citations

Life Sciences, Biochemistry, Pharmacology +13

Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair

Hiroshi Kasai, P. F. Crain, Yoshiyuki Kuchino et al. · Carcinogenesis · 1986 · 923 citations

Medicine, Genetics, Molecular Biology +17

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury.

Katherine J. Kelly, W. W. Williams, R B Colvin et al. · Journal of Clinical Investigation · 1996 · 731 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia–reperfusion injury

Kentaro Hayashida, Motoaki Sano, Ikuroh Ohsawa et al. · Biochemical and Biophysical Research Communications · 2008 · 475 citations

Medicine, Cardiology, Physiology +6

Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress

Kei-ichi Fukuda, Sadamitsu Asoh, Masahiro Ishikawa et al. · Biochemical and Biophysical Research Communications · 2007 · 410 citations

Pharmacy, Biochemistry, Toxicology +16