Evaluation of¹⁸F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

Abstract

Our results indicated that (18)F-UCB-H is a suitable radiotracer for the imaging of SV2A in vivo. To our knowledge, this is the first PET tracer for the in vivo quantification of SV2A. The necessary steps for the implementation of (18)F-UCB-H production under good manufacturing practice conditions and the first human studies are being planned.