Essential function for the calcium sensor STIM1 in mast cell activation and anaphylactic responses

A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

Stefan Feske, Yousang Gwack, Murali Prakriya et al. · Nature · 2006 · 2.2K citations

Crac Channel Function, Immunogenetics, Molecular Immunology +10

STIM Is a Ca2+ Sensor Essential for Ca2+-Store-Depletion-Triggered Ca2+ Influx

Jen Liou, Man Lyang Kim, Won Do Heo et al. · Current Biology · 2005 · 2.1K citations · Full text

Physiology, Ca2+ Sensor Essential

STIM1, an essential and conserved component of store-operated Ca2 <b>+</b> channel function

Jack Roos, Paul J. DiGregorio, Andriy V. Yeromin et al. · The Journal of Cell Biology · 2005 · 1.8K citations · Full text

Depletion of intracellular calcium stores activates a calcium current in mast cells

Markus Hoth, Reinhold Penner · Nature · 1992 · 1.7K citations

Signal Transduction, Molecular Physiology, Cell Signaling +8

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

Ricardo E. Dolmetsch, Richard S. Lewis, Christopher C. Goodnow et al. · Nature · 1997 · 1.7K citations

Transcription Factors, Signal Transduction, Ca2+ Response Amplitude +13