Leptomycin B‐sensitive nuclear export of MAPKAP kinase 2 is regulated by phosphorylation

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

John C. Lee, Jeffrey T. Laydon, Peter McDonnell et al. · Nature · 1994 · 3.3K citations

Life Sciences, Immunology, Molecular Biology +14

Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

Joël Raingeaud, Shashi Kumar Gupta, Jeffrey S. Rogers et al. · Journal of Biological Chemistry · 1995 · 2.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

Ana Cuenda, J.B. Rouse, Yair N. Doza et al. · FEBS Letters · 1995 · 2.1K citations

Life Sciences, Molecular Biology, Pharmacology +14

CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals

Maarten Fornerod, Mutsuhito Ohno, Minoru Yoshida et al. · Cell · 1997 · 2.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

John Rouse, Philip Cohen, Sylviane Trigon et al. · Cell · 1994 · 1.7K citations

Life Sciences, Biochemistry, Molecular Biology +15