Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor<scp>X</scp>a inhibitor - Concepedia

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Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor<scp>X</scp>a inhibitor

DOI Full Paper Access

158

Citations

38

References

2014

Year

Charles Frost, Wonkyung Byon, Yan Song, Jessie Wang, Alan Schuster, Rebecca A. Boyd, Donglu Zhang, Zhigang Yu, Clapton Dias, Andrew Shenker,

British Journal of Clinical Pharmacology

Abstract

A 2-fold and 1.4-fold increase in apixaban exposure was observed with co-administration of ketoconazole and diltiazem, respectively.

References

	Year	Citations

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