Non-random cleavage of SV40 DNA in the compact minichromosome and free in solution by micrococcal nuclease

Detection of specific sequences among DNA fragments separated by gel electrophoresis

E.M. Southern · Journal of Molecular Biology · 1975 · 32.8K citations

Life Sciences, Molecular Biology, Molecular Genetics +12

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

Peter Rigby, Marianne Dieckmann, Carl Rhodes et al. · Journal of Molecular Biology · 1977 · 11.7K citations

Life Sciences, Molecular Biology, Molecular Genetics +14

A membrane-filter technique for the detection of complementary DNA

David T. Denhardt · Biochemical and Biophysical Research Communications · 1966 · 3.9K citations

Life Sciences, Biotechnology, Molecular Biology +13

Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose-ethidium bromide electrophoresis

Phillip A. Sharp, Bill Sugden, Joe Sambrook · Biochemistry · 1973 · 1.6K citations

Life Sciences, Biochemistry, Microbiology +12

Complete nucleotide sequence of SV40 DNA

Walter Fiers, Roland Contreras, Guy Haegeman et al. · Nature · 1978 · 1K citations

Life Sciences, Molecular Biology, Molecular Genetics +4