Biocompatible Carbon Nanotubes Generated by Functionalization with Glycodendrimers

Peng Wu, Xing Chen, Nancy Hu, Un Chong Tam, Ola Blixt, Alex Zettl, Carolyn R. Bertozzi

Angewandte Chemie International Edition · 2008 · 187 citations · 26 references

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Concepts

Abstract

Protective coatings: Glycodendrimers can function as homogeneous bioactive coatings that mitigate the cytotoxicity of single-walled carbon nanotubes (SWNTs). The bifunctional glycodendrimers (see picture) have peripheral carbohydrate units and a pyrene tail capable of binding SWNT surfaces through π–π interaction. Cells cultured with glycodendrimer-coated SWNTs proliferate at the same rate as untreated cells.

References

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