Pyrosequencing of the Genital Microbiotas of HIV-Seropositive and -Seronegative Women Reveals <i>Lactobacillus iners</i> as the Predominant <i>Lactobacillus</i> Species

Abstract

The species of vaginal lactobacilli in HIV-seropositive and -seronegative women were determined by 16S gene pyrosequencing. Lactobacillus iners sequences were the predominant lactobacillus sequences in 66% of HIV(+) women and 90% of HIV(-) women. This has implications for resistance of HIV(+) and HIV(-) women to genital colonization by pathogenic organisms.