Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice - Concepedia

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Disruption of Hypoxia-Inducible Factor 1 in Adipocytes Improves Insulin Sensitivity and Decreases Adiposity in High-Fat Diet–Fed Mice

DOI Full Paper Access

265

Citations

37

References

2011

Year

Changtao Jiang, Aijuan Qu, Tsutomu Matsubara, Tatyana Chanturiya, William Jou, Oksana Gavrilova, Yatrik M. Shah, Frank J. Gonzalez

Abstract

Inhibition of HIF1 in adipose tissue ameliorates obesity and insulin resistance. This study reveals that HIF1 could provide a novel potential therapeutic target for obesity and type 2 diabetes.

References

	Year	Citations

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