Concepedia

A New Active Vitamin D, ED-71, Increases Bone Mass in Osteoporotic Patients under Vitamin D Supplementation: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Toshio Matsumoto, Takami Miki, Hiroshi Hagino, Toshitsugu Sugimoto, Sumiaki Okamoto, Takako Hirota, Yusuke Tanigawara, Yasufumi Hayashi, Masao Fukunaga, Masataka Shiraki,

The Journal of Clinical Endocrinology & Metabolism · 2005 · 139 citations · 12 references

DOIFull text

Open access

Abstract

These results demonstrate that ED-71 treatment at around 0.75 microg/d can effectively and safely increase lumbar and hip BMD in osteoporotic patients with vitamin D supplementation.

References

12

Vitamin D<sub>3</sub>and Calcium to Prevent Hip Fractures in Elderly Women

M C Chapuy, M Arlot, F. Duboeuf et al. · New England Journal of Medicine · 1992 · 2.9K citations · Full text

Diagnostic criteria for primary osteoporosis: year 2000 revision

Hajime Orimo, Yasufumi Hayashi, Masao Fukunaga et al. · Journal of Bone and Mineral Metabolism · 2001 · 463 citations

, , +4

Effects of 1?-hydroxyvitamin D3 on lumbar bone mineral density and vertebral fractures in patients with postmenopausal osteoporosis

H. Orimo, Masataka Shiraki, Yujiro Hayashi et al. · Calcified Tissue International · 1994 · 224 citations

, , +6

Diagnostic criteria of primary osteoporosis

Hajime Orimo, Youichi Sugioka, Masao Fukunaga et al. · Journal of Bone and Mineral Metabolism · 1998 · 209 citations

, , +5

A potent analog of 1α,25-dihydroxyvitamin D <sub>3</sub> selectively induces bone formation

Nirupama K. Shevde, Lori A. Plum, Margaret Clagett‐Dame et al. · Proceedings of the National Academy of Sciences · 2002 · 175 citations · Full text