Concepedia

HER3 Is a Determinant for Poor Prognosis in Melanoma

Markus Reschke, Daniela Mihic‐Probst, Edward H. van der Horst, Pjotr Knyazev, Peter J. Wild, Markus Hutterer, Stefanie Meyer, Reinhard Dummer, Holger Moch, Axel Ullrich

Clinical Cancer Research · 2008 · 166 citations · 38 references

DOIFull text

Open access

Abstract

Our results provide novel insights into the role of HER3 in melanoma and point out new possibilities for therapeutic intervention.

References

38

<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi et al. · Science · 2007 · 4.4K citations

Tissue microarrays for high-throughput molecular profiling of tumor specimens

Juha Kononen, Lukas Bubendorf, Anne Kallionimeni et al. · Nature Medicine · 1998 · 4.1K citations

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A rapid in vitro assay for quantitating the invasive potential of tumor cells.

Adriana Albini, Yukihide Iwamoto, Kleinman Hk et al. · PubMed · 1987 · 1.8K citations

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Rheb Binds and Regulates the mTOR Kinase

Yenshou Lin, Sara Ortiz-Vega, Kazuyoshi Yonezawa et al. · Current Biology · 2005 · 984 citations · Full text

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Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Natalia Sergina, Megan Rausch, Donghui Wang et al. · Nature · 2007 · 968 citations · Full text

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