Journal of Medicinal Chemistry · 2009 · 195 citations · 29 references
Alzheimer’s disease (AD) is a neurodegenerative disease of the brain, characterized by a slowly progressive dementia. This insidious disease is growing in importance because it affects millions of older patients. Clinical symptoms of AD include cognitive decline, irreversible memory loss, disorientation and language impairment. Major neuropathology observations of
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Practice parameter: Diagnosis of dementia (an evidence-based review)
David S. Knopman, Steven T. DeKosky, Jeffrey L. Cummings et al. · Neurology · 2001 · 1.4K citations
Imaging β-amyloid burden in aging and dementia
C. C. Rowe, Sally Ng, Uwe Ackermann et al. · Neurology · 2007 · 1.1K citations