Modulation of the Startle Response and Startle Laterality in Relatives of Schizophrenic Patients and in Subjects With Schizotypal Personality Disorder: Evidence of Inhibitory Deficits

Abstract

These data suggest a genetically transmitted deficit in prepulse inhibition (sensorimotor gating) in patients with schizophrenia spectrum disorders, including subjects with schizotypal personality disorder and relatives of patients with schizophrenia.