Laurence–Moon–Biedl syndrome: renal ultrasound appearances in the neonate

Abstract

Renal disease is now considered one of the cardinal features of the Laurence–Moon–Biedl syndrome (LMBS). The most commonly described radiographic changes are calyceal distortion with cortical and medullary cysts on intravenous urography (IVU). We present two cases of LMBS who, on ultrasound (US) imaging in the neonatal period, had enlarged hyperechoic kidneys indistinguishable from autosomal recessive polycystic kidneys (ARPK). To our knowledge only one such case has previously been reported in the literature (Ritchie et al, 1988).