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Publication | Open Access

A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis

DOIFull Paper Access

164

Citations

42

References

2015

Year

Susan Armstrong, Michael G. Sugiyama, Karen Fung, Yizhuo Gao, Changsen Wang, Andrew Levy, Paymon Azizi, Mark Roufaiel, Su-Ning Zhu, Dante Neculai,
Cardiovascular Research

Abstract

We developed an assay to quantify LDL transcytosis across endothelial cells and discovered an unexpected role for SR-BI. Elucidating the mechanisms of LDL transcytosis may identify novel targets for the prevention or therapy of atherosclerosis.

References

YearCitations

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