IEEE Transactions on Nuclear Science · 2000 · 41 citations · 12 references
EngineeringBiomedical EngineeringRadiologyBiomedical ImagingDiagnostic ImagingDiagnostic RadiologyGamma-ray DetectionGamma-ray DetectorsRadiation Detector ArraysRadiation Imaging DetectorsRadiation Imaging SystemsRadiographic ImagingCollimator DesignCompact Module DesignDetector ArraysGamma-ray ImagingHigh-resolution ImagingImaging ResolutionLaminar CompositesSemiconductor Detector Arrays
The poor performance of current parallel-hole collimators is an impediment to planar high-resolution gamma-ray imaging, even when high-resolution semiconductor detector arrays are available. High-resolution parallel-hole collimators are possible but have not been fabricated because conventional collimator construction techniques severely limit achievable bore size and septal thickness. We describe development and testing of a high-resolution collimator with 4096 260-/spl mu/m square bores and 380 /spl mu/-m pitch, matched to our existing 2.5 cm/spl times/2.5 cm hybrid 64/spl times/64 CdZnTe arrays with multiplexer readout. The collimator is a laminar composite of about 100 layers of W sheets produced by photolithography and has an efficiency of 5/spl times/10/sup -5/. We have demonstrated sub-millimeter spatial resolution at 140 keV in both phantom and animal imaging using this system. We present images of resolved individual vertebrae in the spine of a mouse and lymphatic channels and nodes in a rat. The collimator and semiconductor array could form a compact module for use in a wide variety of gamma-ray imaging systems.
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MicroPET: a high resolution PET scanner for imaging small animals
Simon R. Cherry, Yiping Shao, Robert W. Silverman et al. · IEEE Transactions on Nuclear Science · 1997 · 615 citations
Comparison of fluorine-18-FDG PET and thallium-201 SPECT in evaluation of lung cancer.
Kotaro Higashi, Tadaaki Nishikawa, Hiroaki Seki et al. · PubMed · 1998 · 80 citations
CdZnTe solid-state gamma camera
J.F. Butler, C.L. Lingren, S.J. Friesenhahn et al. · IEEE Transactions on Nuclear Science · 1998 · 60 citations
Engineering, Computer Engineering, Electrical Engineering +17