European Journal of Lipid Science and Technology · 2013 · 276 citations · 46 references
Natural SciencesChemical EngineeringChemistryBiocatalysisCatalysisEnzymologySafer SolventsSolution ChemistryDeep Eutectic Solvent CatalysisDeep Eutectic Solvent SynthesisDeep Eutectic SolventsHydrogen Bond Donor-acceptor MixturesIonic Liquid CatalysisIonic LiquidsSolvent Effects On CatalysisSolvent Effects On Reaction Pathways
Abstract In recent years, a novel medium with similar properties to ionic liquids but with additional advantages regarding cost, environmental impact, and synthesis has been developed: deep eutectic solvents (DESs). These solvents result from the association between an organic salt (ammonium or phosphonium) with a hydrogen‐bond donor such as alcohols, acids, or amides. To date, the availability of green, inexpensive and easy to handle solvents is almost non‐existent. Therefore, DESs currently arouse growing interest in many research fields. This review deals with the major applications of this new family of solvents with a particular focus on lipase‐catalyzed reactions such as hydrolysis, aminolysis, or alcoholysis.
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