Concepedia

LIM only 4 is overexpressed in late stage pancreas cancer

Jun Yu, Kenoki Ohuchida, Kohei Nakata, Kazuhiro Mizumoto, Lin Cui, Hayato Fujita, Hiroshi Yamaguchi, Takuya Egami, Hidehisa Kitada, Masao Tanaka

Molecular Cancer · 2008 · 31 citations · 36 references

DOIFull text

Open access

Abstract

Pancreatic carcinomas (both IDC and IPMC) expressed significantly higher levels of LMO4 mRNA than did normal ductal epithelia, PanIN-1B, PanIN-2, IPMA and IPMB. These results suggested that LMO4 is overexpressed at late stages in carcinogenesis of pancreatic cancer.

References

36

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

, , +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

, , +7

Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase

Dieter E. Jenne, Heike Reomann, Jun‐ichi Nezu et al. · Nature Genetics · 1998 · 1.2K citations

, , +11

Pancreatic Intraepithelial Neoplasia

Ralph H. Hruban, Volkan Adsay, Jorge Albores‐Saavedra et al. · The American Journal of Surgical Pathology · 2001 · 1.1K citations

DPC4 gene in various tumor types.

Mieke Schutte, Ralph H. Hruban, Lora Hedrick et al. · PubMed · 1996 · 676 citations

, , +12