Concepedia

Publication | Closed Access

Association of CYP2D microsatellite polymorphism with Lewy body variant of Alzheimer's disease

DOI

33

Citations

0

References

1998

Year

Seigo Tanaka, X. Chen, Yijun Xia, Dae‐Hyun Kang, Naomi Matoh, Mary Sundsmo, Ronald G. Thomas, Robert Katzman, Lean Thal, John Q. Trojanowski,
Neurology

Abstract

The CYP2D locus is closely associated with LBV and PD. The CYP2D6 B mutation may be involved in pathogenesis of LBV and PD in a dominant-negative manner, or in the linkage disequilibrium of the CYP2D microsatellite to another pathogenic gene locus.