Oximate ion promoted unblocking of oligonucleotide phosphotriester intermediates

Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides¹

Jacek Stawiński, Toyoharu Hozumi, Saran A. Narang et al. · Nucleic Acids Research · 1977 · 234 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +17

Improved triester approach for the synthesis of pentadecathymidylic acid

K. ITAKURA, N. KATAGIRI, Chander P. Bahl et al. · Journal of the American Chemical Society · 1975 · 110 citations

Natural Sciences, Chemistry, Analytical Chemistry +4

Synthesis of oligonucleotides with sequences identical with or analogous to the 3′ - end of I6S ribosomal RNA of Escherichia coli: preparation of A-C-C-U-C-C via the modified phosphotriester method¹

Jacques H. van Boom, Peter Burgers, G. van der Marel et al. · Nucleic Acids Research · 1977 · 70 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +16

The application of levulinic acid as protective group to the synthesis of tetradecaribonucleotide U‐A‐U‐A‐U‐A‐U‐A‐U‐A‐U‐A‐U‐A <i>via</i> the modified phosphotriester method

Jacques H. van Boom, Peter Burgers · Recueil des Travaux Chimiques des Pays-Bas · 1978 · 65 citations

Pharmacy, Biochemistry, Enzymology +11

The phosphotriester approach to oligonucleotide synthesis: preparation of oligo- and poly-thymidylic acids

R. Arentzen, Colin B. Reese · Journal of the Chemical Society Perkin Transactions 1 · 1977 · 43 citations

Pharmacy, Biochemistry, Chemistry +13