Correction of partial-volume effect for PET striatal imaging: fast implementation and study of robustness.

Abstract

A simple but efficient implementation in the image space of the GTM method yields accurate PVE correction in striatal regions in studies with 3D PET and enables clinical use. The method is less sensitive to residual misregistration errors between PET and anatomy than to residual missegmentation of the anatomy. Special care should be taken with segmentation of the regions to correct for PVE.