Concepedia

Telomerase as a therapeutic target in cancer

Ginelle C. Gellert, Shalmica R. Jackson, Z. Günnur Dikmen, Woodring E. Wright, Jerry W. Shay

Drug Discovery Today Disease Mechanisms · 2005 · 36 citations · 31 references

DOI

Concepts

References

31

The G-Quadruplex-Interactive Molecule BRACO-19 Inhibits Tumor Growth, Consistent with Telomere Targeting and Interference with Telomerase Function

Angelika M. Burger, Fangping Dai, Christoph Schultes et al. · Cancer Research · 2005 · 566 citations · Full text

, , +15

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

Sheila A. Stewart, William C. Hahn, Benjamin F. O’Connor et al. · Proceedings of the National Academy of Sciences · 2002 · 428 citations · Full text

, , +17

Effects of Reverse Transcriptase Inhibitors on Telomere Length and Telomerase Activity in Two Immortalized Human Cell Lines

Catherine Strahl, Elizabeth H. Blackburn · Molecular and Cellular Biology · 1996 · 338 citations · Full text

, , +14

Telomerase-Specific Replication-Selective Virotherapy for Human Cancer

Takeshi Kawashima, Shunsuke Kagawa, Naoya Kobayashi et al. · Clinical Cancer Research · 2004 · 261 citations · Full text

, , +15

Vaccination of Cancer Patients Against Telomerase Induces Functional Antitumor CD8+ T Lymphocytes

Robert H. Vonderheide, Susan M. Domchek, Joachim L. Schultze et al. · Clinical Cancer Research · 2004 · 254 citations

, , +17