A Case of Levetiracetam (Keppra®) Poisoning with Clinical and Toxicokinetic Data

Abstract

In overdose, levetiracetam is sedating and causes respiratory depression, however, recovery is rapid with supportive care. This is the first reported case of levetiracetam overdose; serial serum concentrations suggest first-order elimination even at concentrations 10-40 fold higher than therapeutic.