Concepedia

A versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones

Claire E. T. Mitchell, Stacey E. Brenner, Steven V. Ley

Chemical Communications · 2005 · 119 citations · 27 references

DOI

Concepts

Abstract

5-Pyrrolidin-2-yltetrazole performs as an improved catalyst for the asymmetric addition of a range of nitroalkanes to cyclic and acyclic enones, with good to excellent enantioselectivity.

References

27

Recent Advances in Catalytic Enantioselective Michael Additions

Norbert Krause, Anja Hoffmann‐Röder · Synthesis · 2001 · 946 citations

, , +13

Enantioselective Conjugate Additions

Mukund P. Sibi, S. Manyem · Tetrahedron · 2000 · 811 citations

Enantioselective Organocatalytic Indole Alkylations. Design of a New and Highly Effective Chiral Amine for Iminium Catalysis

Joel F. Austin, David W. C. MacMillan · Journal of the American Chemical Society · 2002 · 620 citations

, , +14

Asymmetric Direct Aldol Reaction Assisted by Water and a Proline‐Derived Tetrazole Catalyst

Hiromi Torii, Masakazu Nakadai, Kazuaki Ishihara et al. · Angewandte Chemie International Edition · 2004 · 568 citations

, , +12

Organocatalysis with proline derivatives: improved catalysts for the asymmetric Mannich, nitro-Michael and aldol reactions

Alexander J. A. Cobb, David M. Shaw, Deborah A. Longbottom et al. · Organic & Biomolecular Chemistry · 2004 · 488 citations

, , +6