Concepedia

The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer Subtypes

Aurélie Docquier, Pierre-Olivier Harmand, Samuel Fritsch, Maïa Chanrion, Jean-Marie Darbon, Vincent Cavaillès

Clinical Cancer Research · 2010 · 59 citations · 24 references

DOIFull text

Open access

Abstract

This study shows that RIP140 is a regulator of the E2F pathway, which discriminates luminal- and basal-like tumors, emphasizing the importance of these regulations for a clinical cancer phenotype.

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