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The HLA-DR3,DQ2 Heterozygous Genotype is Associated with an Accelerated Progression of Primary Sclerosing Cholangitis

DOI

67

Citations

23

References

2001

Year

K.M. Boberg, Anne Spurkland, Giorgia Della Rocca, Thore Egeland, S. Saarinen, Sara H. Mitchell, Ulrika Broomé, Roger W. Chapman, Olle Olerup, Albert Parés,
Scandinavian Journal of Gastroenterology

Abstract

The DR3,DQ2 heterozygous genotype is associated with a more rapid progression of PSC, whereas HLA-DQ6 is associated with a retarded disease progression. It is possible that the DR4,DQ8 haplotype is related to cholangiocarcinoma development.

References

YearCitations

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