Concepedia

Autocrine TNFα Signaling Renders Human Cancer Cells Susceptible to Smac-Mimetic-Induced Apoptosis

Sean L. Petersen, Lai Wang, Asligul Yalcin-Chin, Lin Li, Michael Peyton, John D. Minna, Patrick G. Harran, Xiaodong Wang

Cancer Cell · 2007 · 571 citations · 36 references

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36

Use of Chemotherapy plus a Monoclonal Antibody against HER2 for Metastatic Breast Cancer That Overexpresses HER2

Dennis J. Slamon, Brian Leyland‐Jones, Steven Shak et al. · New England Journal of Medicine · 2001 · 11.5K citations · Full text

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Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

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An inhibitor of Bcl-2 family proteins induces regression of solid tumours

Tilman Oltersdorf, Steven W. Elmore, Alexander R. Shoemaker et al. · Nature · 2005 · 3.4K citations

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NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation

Cun-Yu Wang, Marty W. Mayo, Robert G. Korneluk et al. · Science · 1998 · 2.7K citations · Full text

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Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.7K citations · Full text

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