Concepedia

Publication | Open Access

Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen

DOIFull Paper Access

107

Citations

48

References

2001

Year

A. A. Shah, Frank E. Murray, E. Kay, Mary Barry, G Sigthorsson, H Gudjónsson, Einar Oddsson, Ashley B. Price, Desmond J. Fitzgerald, Ingvar Bjarnason
Gut

Abstract

Nimesulide has preferential selectivity for COX-2 over COX-1 in vivo at full therapeutic doses and induces less gastrointestinal damage than that seen with naproxen in the short term.

References

YearCitations

Page 1