Tumor lysis syndrome in patients with acute myeloid leukemia: identification of risk factors and development of a predictive model

Abstract

TLS is frequently observed in AML patients during induction therapy. Only the development of CTLS had an impact on higher mortality rate from induction therapy. The scoring system derived from this study can be used to obtain an accurate estimate of the individual risk of TLS, allowing for risk-adapted prophylaxis against this complication.