Inhibition of Buthionine Sulfoximine-Enhanced Doxorubicin Toxicity in Metallothionein Overexpressing Transgenic Mouse Heart

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

Frank Tietze · Analytical Biochemistry · 1969 · 6.1K citations

Life Sciences, Biochemistry, Analytical Chemistry +14

Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals

Paul J. Thornalley, Milan Vašák · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1985 · 1K citations

Life Sciences, Radiation Oncology, Toxicology +16

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis.

Owen W. Griffith · Journal of Biological Chemistry · 1982 · 701 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

A general mechanism for microsomal activation of quinone anticancer agents to free radicals.

Nicholas R. Bachur, Sandra Gordon, Malcolm V. Gee · PubMed · 1978 · 640 citations

Medicine, Biochemistry, Pharmacology +16

Overexpression of Metallothionein Confers Resistance to Anticancer Drugs

Susan L. Kelley, Alakananda Basu, Beverly A. Teicher et al. · Science · 1988 · 605 citations

Medicine, Oncology, Pharmacology +13