Cellular Retinoic Acid Bioavailability Determines Epithelial Integrity: Role of Retinoic Acid Receptor α Agonists in Colitis

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

Gerald P. Morris, Paul L. Beck, Margaret S. Herridge et al. · Gastroenterology · 1989 · 1.7K citations

Life Sciences, Immunology, Physiology +16

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

Life Sciences, Immunology, Pathology +17

Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines

Levinus A. Dieleman, Mary Palmen, Halil Akol et al. · Clinical & Experimental Immunology · 1998 · 1.2K citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

Antony J. Durston, J. P. M. Timmermans, W. J. Hage et al. · Nature · 1989 · 887 citations

Life Sciences, Developmental Biology, Neurobiology +10

A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response

Chinyu Su, Xiaoming Wen, Shannon T. Bailey et al. · Journal of Clinical Investigation · 1999 · 758 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17