STUDIES ON A LUNG TISSUE COMPONENT WHICH COMBINES WITH PNEUMONIA VIRUS OF MICE (PVM)

Abstract

Evidence has been obtained which indicates that the lung tissues of mammalian species susceptible to infection with PVM contain a specific component which combines with the virus. The concentration of this tissue component appears to be directly proportional to the suceptibility of the species; in its absence infection with PVM cannot be established. The available evidence suggests that the presence of the virus-combining component in lung tissue may play a decisive ro1e in the initiation of infection with this pneumotropic virus.