Concepedia

Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: <i>In Vitro</i> and <i>In Vivo</i> Evidence

Maria Teresa Di Martino, Emanuela Leone, Nicola Amodio, Umberto Foresta, Marta Lionetti, Maria R. Pitari, Maria Eugenia Gallo Cantafio, Annamaria Gullà, Francesco Conforti, Eugenio Morelli,

Clinical Cancer Research · 2012 · 243 citations · 36 references

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Abstract

Our findings provide a proof-of-principle that formulated synthetic miR-34a has therapeutic activity in preclinical models and support a framework for development of miR-34a-based treatment strategies in MM patients.

References

36

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