Fine‐needle aspiration cytology of extranodal natural killer/T‐cell lymphoma

José A. Jiménez‐Heffernan, Pilar González‐Peramato, Cristian Perna, Javier Alvarez‐Ferreira, Pilar López‐Ferrer, José M. Viguer

Diagnostic Cytopathology · 2002 · 19 citations · 8 references

Concepts

Abstract

Extranodal NK/T-cell lymphoma, nasal type, is a predominantly extranodal lymphoma characterized histologically by prominent necrosis, angiocentric growth, and vascular destruction. Only one report describing its fine-needle aspiration (FNA) cytologic features is available and shows highly unusual findings for a lymphoma. The present case concerns a 58-yr-old patient that presented with a soft tissue mass of the thigh in addition to an ulcerative lesion of the palate and nodular hepatic and splenic lesions. FNA cytology of the thigh tumor was interpreted as a malignant mesenchymal lesion (sarcoma). The subsequent pathologic study revealed an NK/T-cell lymphoma. Our findings are very similar to those previously reported. They were highly unusual for a lymphoma and consisted of polymorphic, round to spindle neoplastic cells distributed in irregular aggregates, and single cells. No significant number of lymphoglandular bodies were present.

References

8